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abundant protein actin actin binding proteins actin filaments acute phase proteins adaptive immune system allergy immunology antibodies antigen apoptosis atp autoimmune diseases b cells b lymphocyte basic immunology biotech company broad branch card 1 catalytic domain cell mediated immunity cell motility cells tissues cellular components cellular processes chip chip-ip kits chromatin immunoprecipitation chronic disorders construction kit contractile apparatus ctls cytoskeleton death domain defense against infectious organisms detection kits disease processes dna binding domain eastern india effectors elisa kits factor binding foxp3 gene expression greek word hexokinase histones hsp70 humoral immune response hydrolysis of atp imgenex corporation immune immune functions immune system attacks immunology india pvt ltd inflammatory conditions innate immune system lymphokines magnesium ions mast cells microfilaments muscle cells muscular contraction natural defence natural killer cells negative selection neurodegenerative diseases nireblog orissa phosphorylate plasm principal types programmed cell death proteases random process regulatory factors regulatory t-cells repressor rna interference salt concentration salt concentrations san diego usa sequential manner signaling pathways somatic cell t lymphocytes target temporal expression thin filaments tissues transcription factor transcription factors transcription machinery transcriptional factors transcriptional repression tumor necrosis factor type hypersensitivity typical eukaryotic cell uv damage zinc finger
17-04-2008 » As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act either as a phosphatase or kinase inhibitor in a contextually dependent manner. Growing evidence points to DARPP-32 as a key [...]
17-04-2008 » All the cellular processes in living cells such as growth, development, morphogenesis and cellular differentiation are a product of gene expression programs involving complicated transcriptional regulation of several genes. This process of transcriptional regulation is tightly controlled and coordinated by proteins called transcriptional regulators. These transcriptional regulators and factors are [...]
17-04-2008 » Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the immune response, the immune system attacks organisms and [...]
17-04-2008 » Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). For more details read out the article: Coined in the 1960's,apoptosis is derived [...]
17-04-2008 » Early development and differentiation of nascent T cells that migrate from bone marrow to become mature, naïve T cells, which are capable of responding to antigen takes place inside the thymus. Around 1010 TCR (T cell receptor) variations are generated in developing T lymphocyte clones through a random process of [...]
17-04-2008 » Actin is a ubiquitous protein involved in the formation of filaments that are major components of the cytoskeleton. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments which are part of the contractile apparatus in muscle cells. It is [...]
17-04-2008 » Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are important molecules in mammalian cellular signaling. The three widely expressed isoforms of PKB (PKB , PKBß and PKB ; also known as Akt1, Akt2 and Akt3, respectively) [...]
17-04-2008 » ATM, the gene product mutated in the cancer susceptibility syndrome ataxia–telangiectasia, is related to proteins involved in DNA repair and cell-cycle control. It encodes a nuclear 350 kDa phosphoprotein containing a carboxy terminus phosphatidylinositol 3-kinase (Pl-3 kinase) catalytic domain shared by members of a superfamily of large eukaryotic proteins involved [...]
17-04-2008 » FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function. FOXP3 significance in the normal development of Tregs is better elucidated with the fact that mutated FOXP3 results in a rare and fatal early onset autoimmune disorder [...]
17-04-2008 » RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals. The RNAi pathway is thought to be an ancient mechanism for protecting the host and its genome against viruses and [...]
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