2008-04-17 » Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are important molecules in mammalian cellular signaling. The three widely expressed isoforms of PKB (PKB , PKBß and PKB ; also known as Akt1, Akt2 and Akt3, respectively) [...]