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Tag » Blog: "stephenjones" » Tag: "catalytic domain"

Akt Family: Antibodies from Imgenex

2008-04-17 » Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are important molecules in mammalian cellular signaling. The three widely expressed isoforms of PKB (PKB , PKBß and PKB ; also known as Akt1, Akt2 and Akt3, respectively) [...]

ATM (Ataxia Telangiectasia Mutated) Antibodies from Imgenex

2008-04-17 » ATM, the gene product mutated in the cancer susceptibility syndrome ataxia–telangiectasia, is related to proteins involved in DNA repair and cell-cycle control. It encodes a nuclear 350 kDa phosphoprotein containing a carboxy terminus phosphatidylinositol 3-kinase (Pl-3 kinase) catalytic domain shared by members of a superfamily of large eukaryotic proteins involved [...]

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