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Tag » Blog: "stephenjones" » Tag: "imgenex corporation"

Faces of DARPP-32: Master Signaling Mediator in the Brain?

2008-04-17 » As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act either as a phosphatase or kinase inhibitor in a contextually dependent manner. Growing evidence points to DARPP-32 as a key [...]

Apoptosis Programmed Cell Death.

2008-04-17 » Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). For more details read out the article: Coined in the 1960's,apoptosis is derived [...]

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